Research Investigator, Drug Metabolism

at Company: Infinity Pharmaceuticals, Inc. in Job Category: Pharmacology
posted on 9/8/08 12:00am

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Company
Infinity Pharmaceuticals, Inc.

Contact Name:
Recruitment

Website:
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Job Reference Code:
08-0027

Research Investigator, Drug Metabolism

Infinity Pharmaceuticals is an innovative cancer drug discovery and development company that is seeking to leverage its strength in small molecule drug technologies to discover, develop, and deliver to patients first-in-class or best-in-class medicines for the treatment of cancer and related conditions.


Position Deliverables:
The position of Research Investigator, Drug Metabolism requires an understanding of the theory and practice of in vitro and in vivo drug metabolism studies. The individual, with supervision, will primarily design and perform a variety of drug metabolism studies in support of our drug discovery and development efforts. Hands-on experience with enzyme phenotyping, metabolite structural elucidation, and CYP450 inhibition is strongly desired. Knowledge of pharmacokinetic principles is desirable as the individual may provide support as needed. The successful candidate will be responsible for applying different scientific skills including assay development and LC-MS/MS operation. The selected individual will work closely with DMPK team members to analyze and interpret data which will be presented in a multidisciplinary team environment. Qualities vital to our success include flexibility, open communication, and teamwork.
Position Requirements:
• BS/MS in Analytical Chemistry, Biochemistry or related field with 5-10 years experience.
• Extensive experience with a variety of drug metabolism studies, e.g. metabolic stability and metabolite profiling in microsomes, hepatocytes or biological samples from in vivo studies.
• Experience in LC-MS/MS operation, method development, maintenance, and troubleshooting.
• Strong interpersonal skills.
• Strong oral and written communication skills.

Candidates who are technically oriented, creative, organized and have excellent analytical skills are encouraged to apply.


Infinity offers an outstanding benefits package and is an EOE.

Qualified candidates are encouraged to apply online at www.ipi.com/careers/html

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