Global Medical Affairs Business Operations Manager

Shire Pharmaceuticals

Clinical

September 9, 2010

Primary Role:

Provides leadership to the financial management group within Global Medical Affairs and is responsible for the overall management of the financial functions including budget forecasting, cost analysis, and periodic reporting. Partners with the contract management group to support the evaluation, selection and performance review of vendors.

Responsibilities:

30% Budget Development, Forecasting and Management

• Manages the GMA Annual Budget Development as well as Quarterly Budget Reviews and Long Range Plan activities.

• Oversees the management of departmental budget timelines.

• Acts as department Administrator of HGT’s budgeting software package.

• Supports the Senior Director and Manager of GCMA Operations in all budget presentations to Senior Staff and Finance; attends all budget planning and review meetings.

• Collaborates with members of Finance to achieve individual forecasting goals for the department.

• Partners with clinical program leads to develop study-specific budget reporting including top-level analysis, clinical site budget templates, benchmark tracking and analysis.

20% Financial Reporting

• Oversees and manages routine monthly departmental reporting including time allocation, current headcount allocation, credit card statements, and open commitments.

• Develops reports on various financial functions including departmental and study-specific actual vs. budget expenditures.

• Attends periodic financial review meetings with senior departmental staff.

15% Monthly Accrual Reporting / Invoice and Purchase Order Management

• Manages the monthly accruals process and monthly accounting documentation associated with accruals (prepay schedule, recoding of expenses, project-specific supporting documentation).

• Oversees monthly accrual review meetings with appropriate staff within GMA.

• Reviews GMA contract budgets for accurate reporting on cost and deliverables.

• Manages the partnership with the contracts team to ensure accurate purchase order creation and revision. When appropriate, provides guidance on appropriate budget targets or hourly rates.

• Manages GMA’s open commitments on a quarterly basis.

• Develops departmental processes and communicates regularly with senior members of the accounting department to ensure appropriate processes are established and followed.

15% Personnel management

• Responsible for direct line management for 1-4 employees within the financial management team.

• Responsible for performing periodic performance reviews and annual goal setting.

• Effectively and continually prioritizes group’s work load to meet the needs of the department.

10% Vendor Selection and Management

• Participates in the RFP process established by the contract group

• Reviews vendor proposals and attends bid defense meetings. Measures vendors’ capabilities against proposed project budget totals.

• Ensures consistency in pricing across programs. Collaborate with Procurement, Contracts Operations and the program team to identify appropriate costs and services.

10% Implementation of Policies and Procedures

• Enhances department capabilities through improved process oversight.

• Thinks creatively to create efficiencies within the department.

• Has a sophisticated understanding of Shire’s corporate responsibilities and procurement policies as they relate to vendor payment and management

• Interacts with key members of Procurement, Accounting and GMA Operations to ensure consistency across programs.

• Ensures proper training of GMA on all relevant procedures

Education & Experience Requirements:

BA/BS required, MS, MBA preferred. 5-7 years of related financial experience. Clinical and/or Medical Affairs experience required.

Key Skills and Competencies:

Skills and Competencies:

• Strong knowledge of the drug development process.

• Strong organizational and planning skills.

• Ability to communicate effectively in a fast-paced environment.

• Ability to work in a team environment under high pressure situations.

• Proficient with Microsoft Office Leadership DNA:

• Global and cross boundary communication reinforcing the expectation of collaborative behavior and enabling teams to be successful

• Accountability and ownership for end results despite potential barriers to success

• Looks for efficiencies and continuous improvement by questioning whether all activities are necessary to maintain high productivity

Complexity and Problem Solving:

• Defines departmental practices and policies as they relate to the job function to provide colleagues and staff with tools and techniques for obtaining desired outcomes.

• Identifies and understands individual development needs and provides feedback to improve performance.

• Represents the group in providing solutions to difficult technical/functional issues associated with specific projects. Failure to obtain results or erroneous decisions or recommendations would typically result in serious delays and require considerable resources to correct.

Internal and External Contacts:

• Internal interaction with Accounting, Procurement, Medical Affairs and Clinical Affairs Staff

• External contacts include CROs, laboratories, clinical investigative sites, insurance brokers, and others as necessary.

Other Requirements:

Less than 10% domestic and international travel

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