Clinical Pharmacologist I/ Associate Program Lead- Clinical Pharmacology
Vertex Pharmaceuticals, Inc. is looking for a Clinical Pharmacologist to join the team in Cambridge MA. The Clinical Pharmacologist I will perform highly scientific functions in support of the company’s Clinical Pharmacology area with some guidance and mentoring on new and complex issues. He/She will complete assigned work in a resourceful, self-sufficient manner and will be able to create alternative approaches to achieve desired results if needed. The candidate will have a good knowledge of related disciplines which interact with the Clinical Pharmacology activities.
The Clinical Pharmacologist I/Associate Program Lead assists with clinical pharmacology plans under the guidance of a program lead, including scientific and operational aspects. He/she assists with clinical pharmacology plans. He/she performs primary analyses as appropriate.
-Contribute to clinical pharmacology plans including drug-drug interaction, special population and safety studies
-Guide protocol concepts and protocol start-up including site initiations and investigator meetings
-Guide program progression including protocol conduct and data analyses
-Guide metabolic, co-dosing and drug-drug interaction issues, collaborating closely with cross functional colleagues
-Contribute to regulatory and safety documents
-Participate in study teams until study start up
-Assist in contract research organization management
-Serve on cross-functional committees as appropriate and contribute to departmental initiatives
-Collaborate internally to ensure appropriate program representation and timely data analysis workstreams
-Contribute to clinical pharmacology summary documents
-Perform PK analyses or guide program analysts in such analyses
-Perform PK/PD or exploratory analyses or guide such analyses as appropriate
-Assist with modeling and simulation plans
-Guide analytical reports including clinical study reports
-Maintain a high standard for good clinical practice, compliance and ethics
-Contribute to publications and abstracts
The Clinical Pharmacologist I/Associate Program Lead will possess strong communication skills. He/she will take a proactive approach to problem solving, assisting with the development of options and risk mitigation. He/she will ensure timely and clear internal, cross-functional and management communications and will routinely exchange ideas in small settings. He/she will prioritize effective cross-functional interactions to spur innovation. He/she will deliver effective written deliverables including slide presentations. He/she will work comfortably in a matrix system and build a network. He/she will provide guidance to clinical pharmacology data analysts. In all of these activities, he/she will demonstrate leadership skills.
-Ph.D. in Pharmacokinetics, Pharmaceutical Sciences, or other life sciences or Pharm.D.
-1-5 years experience in the Biotechnology/ Pharmaceutical Industry or post-doctoral training.
-Strong fund of knowledge in metabolism and clinical aspects of drug interactions
-Thorough understanding of PK principles and strong experience in NCA analyses
-Exhibits ability to independently interpret and integrate preclinical PK/PD information into the design, conduct and analysis of preclinical, clinical pharmacology and biopharmaceutical studies.
-Communicates effectively in verbal presentations and in writing technical reports
-Embody the Vertex Core Values of Uncompromising Commitment to Patients, Fearless Pursuit of Excellence, Innovation is Our Lifeblood, and “We” Wins
-Effective communication skills, both verbal and written
-Ability to navigate and be successful in a fast-paced, highly-matrixed work environment
-A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society
Vertex creates new possibilities in medicine. Our team discovers, develops and commercializes innovative therapies so people with serious diseases can lead better lives. Vertex scientists and our collaborators are working on new medicines to cure or significantly advance the treatment of hepatitis C, cystic fibrosis, rheumatoid arthritis and other life-threatening diseases. Founded more than 20 years ago in Cambridge, Mass., we now have ongoing worldwide research programs and sites in the United States, United Kingdom and Canada. Vertex has consistently been recognized as one of the industry's top workplaces by leading publications such as Science magazine, The Boston Globe, Boston Business Journal, San Diego Business Journal and The Scientist. For more information and to view Vertex's press releases, please visit www.vrtx.com.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
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