Assistant Director, Computational Lab
The Broad Technology Labs (BTL) is a multi-disciplinary group whose goal is to develop new advanced technologies and to provide technical capabilities in collaborative projects. BTL includes a Molecular Biology Lab, a Process and Microfluidic Devices Lab, and a Computational Lab, the latter to be lead by the assistant director for computation.
Key areas of BTL focus include development of a synthetic biology platform, development of innovative molecular biology methods and development of novel microdevices for a range of applications.
The Computational Lab provides a range of support to BTL projects, including rapid prototyping analytical tools, analysis and feedback in support of laboratory development projects, implementation of existing analytical tools, development of new analytical algorithms, and building and support of software infrastructure including data processing pipelines for large scale laboratory processes. Members of the Computational Lab should have the range of expertise required including computational biology, informatics and software engineering. The assistant director serves as a member of the BTL leadership group, and participates in defining scientific and analytical direction and vision for the group, and further provides experience, advice and oversight on computational and software engineering issues within the BTL and in collaborative projects.
This includes taking an active role in developing new development projects, approaches and collaborations. The assistant director will participate in identifying funding opportunities and grant writing, and represent the BTL and Broad through scientific presentations, publications, and funding reports.
- Direct the strategic planning and organizational structure of the Computational Lab.
- Work with BTL leadership including Director, Scientific Director and other BTL leadership to define scientific and analysis direction across the range of BTL projects.
- Drive cutting edge science through participation in a variety of research activities involving scientists within and outside Broad.
- Translate BTL strategic directions into tactical plans as required by individual project and program needs; allocate and direct work across the Computational Lab in support of those goals and ensure appropriate hardware and software infrastructure is in place to meet goals.
- Oversee and participate in rapid prototyping and development of analytical tools, analysis and feedback in support of laboratory development projects.
- Oversee and direct implementation of analytical tools and building and support of software infrastructure required for BTL goals.
- Oversee the software engineering component, such as building scalable pipelines for analysis of massively parallel lab data generation processes.- Work with software engineers, team leaders and project scientists to define requirements, identify existing tools and prioritize new development needed to meet long term and short term scientific goals.
- Work with Co-Director, GSAP and other GSAP leadership to identify funding opportunities, participate in grant-writing and other fund raising activities.
- Represent BTL activities through scientific presentations, publications, and funding agency reports. - Represent BTL needs and interests to funding agencies, partner institutions and collaborators as required.- Other related responsibilities as necessitated by the position.
- Supervises one senior computational biologist and one senior software engineer in a group of 3. Group is expected to grow, perhaps significantly, as new funding sources are engaged.
- Ph.D. or Master’s degree in Computer Science, Life Sciences, Bioinformatics or related discipline required.
- Industry experience preferred, especially in managing computational analysis in R&D environments supervising medium scale (3-5) person teams.
- A minimum of 8 years experience in research or industry required, preferably in a genomics center and/or corporate environment with experience in a variety of systems and approaches.
- Proven success in developing and applying informatic and computational tools including novel algorithms, and in developing and maintaining systems for high throughput data production and analysis required.
- Significant experience developing, organizing, and managing research teams.
- Significant project management experience required.
- Proven leadership skills and ability to direct large-scale collaborative efforts between collaborating groups and centers.
- Excellent oral and written communication skills and the ability to develop internal and external collaborations and promote collaboration and cooperation among teams. Experience in budget management a plus.
- Working knowledge of genomics and/or molecular biology, an understanding of DNA sequencing and related analytical tools required.
- Experience with genome analysis, synthetic biology a plus.
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