Senior Statistical Programmer
Senior Statistical Programmer (Vertex Pharmaceuticals Incorporated; Boston, Massachusetts): Provide technical leadership and support to our Statistical Programming group by applying experience with the SAS statistical programming language and suite of tools, along with proven experience working with CDISC standards and the relevant statistical analysis methodologies in a clinical trial environment. Delegate tasks appropriately and track their progress. Construct estimates of project resource requirements and time lines, as required; and, brief management on accomplishments, status of projects, and any related issues.
Act as a designated member of clinical sub-team(s) in the role of project lead Statistical Programmer for selected studies. Must have solid skills in oral and written communication suitable for a multidisciplinary team environment. Specific duties include: design and code SAS programs for assigned project(s), consistently meeting project objectives; work with the SAS programming language and related tools (e.g., BASE SAS, SAS/STAT, SAS/GRAPH and Macros) to design and code SAS programs; code complex SAS programs for applications designed to analyze and report complex clinical trial data for electronic submissions of data in CDISC format; perform QC checks of advanced SAS code and output produced by other statistical programmers; maintain a working knowledge of relevant medical data, the design and phases of clinical trials, statistics, relevant regulatory requirements, and advances in the pharmaceutical industry; identify problems and develop global tools (e.g., macros) to increase the efficiency and capacity of the Statistical Programming group; brief the internal scientific community and external parties (e.g., CROs, vendors, FDA and others); manage project timelines and schedules for specific phases of projects; may supervise other statistical programming staff.
Minimum requirements are: M.Sc. (or equivalent degree) in statistics, biology, biomedical engineering or relevant life science that includes relevant coursework in statistics, plus 3 years of experience, either in the position offered or in a relevant clinical statistical programming role. In the alternative, will consider qualified applicants with a relevant B.Sc. (or equivalent degree) and at least 5 years of relevant work experience.
Must have: demonstrable advanced knowledge of electronic submissions and related CDISC standards; demonstrable advanced programming experience with all relevant SAS programming for Base Procedures Macros and options commonly used in clinical trial reporting, including the Macro language, BASE SAS, SAS/STAT and SAS/GRAPH; proven experience in a Phase II / III clinical trial environment working with data collection, statistical analysis and interpretation, as well as compliance with the relevant regulatory requirements; proven theoretical knowledge of the relevant methodologies for statistical analysis such as significance testing, regression analysis, multivariate analysis; solid skills in oral and written communication suitable for a multidisciplinary team environment.
Vertex creates new possibilities in medicine. Our team discovers, develops and commercializes innovative therapies so people with serious diseases can lead better lives. Vertex scientists and our collaborators are working on new medicines to cure or significantly advance the treatment of hepatitis C, cystic fibrosis, rheumatoid arthritis and other life-threatening diseases. Founded more than 20 years ago in Cambridge, Mass., we now have ongoing worldwide research programs and sites in the United States, United Kingdom and Canada. Vertex has consistently been recognized as one of the industry's top workplaces by leading publications such as Science magazine, The Boston Globe, Boston Business Journal, San Diego Business Journal and The Scientist. For more information and to view Vertex's press releases, please visit www.vrtx.com.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
HOW TO APPLY:
Apply by resume only to Lauren O’Hearn, Senior Associate, Human Resources, Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210. Reference: CV-042014. No phone calls, please.