R&D Associate II - Product Discovery

University of Massachusetts Medical School


July 21, 2014

The R&D Associate II is responsible for conducting laboratory based research with minimal supervision to support monoclonal antibody development.

Job Requirements


  • Performs splenic fusions and isolates hybridomas that produce relevant antibodies.
  • Creates, cultures, and maintains stable transgenic cell lines for recombinant protein production and cell based assays.
  • Utilizes various protein purification techniques to purify antibodies and recombinant proteins
  • Utilizes a range of biochemistry and molecular biology techniques to analyze recombinant proteins. Techniques include but are not limited to: PCR, ELISA, Western Blots, subcloning, transfections, and HPLC
  • Performs animal work including immunization, sera collection, sera analysis, tail vein injections and splenic fusions. May conduct experiments using small animal disease models.
  • Records data in research notebooks and report results according to MBL SOPs and procedures.
  • Conducts statistical analysis of data; prepares data analysis for presentation.
  • Prepares written / oral reports for presentation to the research group and senior staff.
  • Troubleshoots malfunctioning equipment and techniques.
  • Effectively works and communicates with other groups in order to accomplish goals.
  • Takes an active role in the organizational aspects of the Product Discovery department such as ordering and equipment repair.
  • Trains other R&D Associates on techniques and instrumentation. May supervise interns and technicians.
  • Performs additional job related duties as required.



  • Requires a bachelor’s degree in Biology or related field with a minimum 2 years of relevant experience or equivalent
  • Ability to follow instructions precisely , recognize deviations, and recommend corrective action within scope of training
  • Capable of moderately complex troubleshooting
  • Computer literate and proficient in MS Word, Excel and other relevant electronic systems
  • Strong problem solving, time management and organizational skills. Demonstrated ability to multitask and consistently meet deadlines
  • Possesses well developed attention to detail, ability to maintain accurate records and excellent proofreading skills
  • Excellent written and verbal communication skills. Ability to communicate effectively with others and to train others.
  • Demonstrated initiative through past experience
  • Ability to work effectively both independently and as a member of a team
  • May require individual to work extended hours on occasion to meet business needs
  • Requires ability to lift 50 lbs using proper lifting technique


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