Senior Scientist (1401912)

Bristol-Myers Squibb


August 28, 2014

Bristol-Myers Squibb is an equal opportunity employer - M/F/Vet/Disability

Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. And driven to make a difference, from innovative research to hands-on community support.  Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.


Bristol-Myers Squibb is a global BioPharma company firmly focused on its Mission to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. BMS delivered 14 new medicines to patients in the past 10 years. Innovation is critical for successfully executing our BioPharma strategy. Bristol-Myers Squibb's pipeline is one of the most innovative in the industry. Our pipeline includes a number of biologics products such as YERVOY®, ORENCIA®, NULOJIX®, and a number of exciting late clinical stage compounds including anti-PD1 mAb.

We embrace a diverse workforce and inclusive culture. The health, safety, professional development, work-life balance and equitable, respectful treatment of our employees are among our highest priorities.

This position is in the Analytical Development and Testing (ADT) group of the Biologics Development organization. As a member of the Drug Product Development Analytics function within ADT, this individual will be responsible for the design and hands-on execution of analytical studies to support structural characterization, comparability, forced degradation, formulation development, and other developments activities of biotherapeutics drug candidates at all stages of clinical development as well as commercial. The analytical techniques include electrophoresis (iCIEF, CE-SDS, SDS-PAGE), HPLC/UPLC (size-exclusion, ion exchange, reverse-phase), and glycan analysis (CE-LIF, HPLC/UPLC-FLR) that may be applied for comprehensive understanding of quality attributes, and protein degradation mechanisms as it relate to drug substance and drug product development.

This individual will be required to present and interpret scientific data, lead technical team activities, contribute to IND, IMPD, BLA, and other regulatory filings, write technical reports and represent the department in matrix team meetings when needed.


•PhD with a minimum of 5 years, or Masters degree with a minimum of 10 years, or BS or equivalent with a minimum 13 years, of relevant experience in biopharmaceutical/biotechnology.

•Knowledge of biologics and industry experience in biologics research/development

•Hands-on experience and expertise in protein analytical methods such as glycan analysis (CE-LIF, HPLC/UPLC-FLR), electrophoresis (iCIEF, CE-SDS, SDS-PAGE), HPLC and UPLC (size-exclusion, ion exchange, reverse-phase)

•Expertise in protein separation and enrichment sciences, protein aggregation, and protein structure and folding

•Excellent communication and interpersonal skills, both written and verbal are required. Experience leading matrix team desired.

•Works independently and collaborates with other groups in ADT and deliver results in line with project and team objectives

•Designs, follows and reviews protocols, scientific methods, and departmental procedures; Organizes and interprets scientific data. Experience in authoring IND, IMPD, BLA, and other regulatory filing documents.

•Trains others on procedures, operations and new technology, or methods

•Proactive at keeping current with and leveraging literature and latest technologies.


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