START WORK IMMEDIATELY in fully-equipped up-and-runinng bio and chem wet lab. Book space for 1-10 people in labs/offices, for stays of 1 week up to 2 years. Can check out anytime with 1 week notice. Just bring your supplies, we provide the rest, including full services (waste disposal, licensure, animal facility, safety and environmental compliance, mail pick-up, free internet, long-distance telephone, glass washing, cleaning, ordering of materials). Optional services include analytical and synthetic chem, routine and customized molecular biology work, animal pharmacology in adjacent vivarium. Larger groups (10-40 people) can be accommodated with 6-8 weeks notice in lab expansion space. Expand and contract your workforce and lab space whenever you wish. The key words are flexible length of stay, 5-star lab space, fully-equpped, ready to go, user friendly, and cost-effective. CONTACT: Andrew Salzman, MD (salzman@luriasci.com or 1-866-925-2871 x.709)

Active biology and chemistry wet lab plus offices

The laboratory is well equipped with standard items such as fume hoods, laminar flow hoods, refrigerators, freezers, incubators, freeze dryers, baths, mixers, shakers, stirrers, heaters, coolers, balances, centrifuges, pipettors, glassware, (high) vacuum pumps, chromatography systems, peristaltic pumps, spectrophotometers and plate readers, microscopes, pH meters, an autoclave, and other miscellaneous items. In addition, there are specialized items, such as  mass-spectrometer, FPLC, electrophoresis equipment, scintillation counter and immunohistochemistry apparatus.

Selected items, in addition to or as examples of the above, are highlighted below according to principal discipline:

 General Laboratory

• Refrigerators & Freezers: Refridgerators (2: SO-LOW, DHF4-30SDFMS), explosion-proof refrigerator (Fisher), glass door refrigerator (True manufacturing, GDM-47), two -70°C freezers (Revco ULT2186-5-D30, So-Low), -20°C freezer (Revco U2016GA14)
• Water purification system, (Millipore Elix5), ice maker (Manitowac QY0134),
• Centrifuges: clinical centrifuge (ICC, Y158), Sorvall centrifuge (DuPont Instruments RC-5B) and rotors, Eppendorf centrifuge (Brinkman 5415B), refrigerated centrifuge (Hermle Labnet Z233MK)
• Balances: analytical balance (Ohaus E02140), 2 top pan balances
• Stirrers & Hotplates: various (Corning, Fisher, IKA)
• Miscellaneous: Sonicator, eppindorf pipettors

Biology

• Multi-well plate reader (Molecular Devices Spectramax 190),
• Spectrophotometer (Beckman DU 640),
• PCR equipment: thermal cycler (MJ research PTC-100), analyser
• Sonic dismembrator (Fisher F60),
• Sorvall centrifuge (DuPont Instruments RC-5B) and rotors,  other centrifuges (as above)
• Electrophoresis apparatus, including multiple vertical and horizontal gel apparatus
• Gel dryer (Bio-Rad 583),
• Nutator (Clay Adams 421105),
• Shakers/baths:  bacterial shaker (New Brunswick G-25), shaking water bath  (Boekel Grant ORS-200), red rocker (Hoefer Scientific PR50), horizontal shaker (American Rotator V R4140), Wheaton roller apparatus (Wheaton 348921UL),
• AKAI FPLC system including AKTA purifier, FRAC-950, P960 sample pump (with air sensor kit), Column Screening Kit, and Reverse Flow Kit.  

Tissue Culture

• Sterile hood (Baker Company, SG-400),
• CO2 Incubators (double) (Forma Scientific, RCO3000D-9-A),
• Microscope (AMSCOPE IN200A-3M),
• Dedicated refrigerator (Franklin industries, FC380)
• Dedicated pipettors, aspirator & general instrumentaion

CHEMISTRY  

• 8 foot dedicated chemistry fume hoods,
• Research Scale glassware (Quark, Chemglass): reactor flasks, condensers, pressure reactors,
• Development Scale Reactors (10 g - 1 Kg): multi-necked reactor vessels, condensers, overhead stirrers, heaters, chillers and accessories (2, 5  & 10 L)
• Chromatography: flash chromatography (Teledyne Isco “Combiflash”), gravity & low pressure chromatography systems
• Rotary evaporators with various condenser options and accessories (Buchi R-124, Heidolph-Brinkman Laborta-4200)
• Circulating chillers (Haake F6, Neslab Coolflow CFT-33) and heaters (VWR 1140S)
• Explosion-proof refrigerator (Fisher)
• Flammable cabinets, stirrers (Corning, VWR)

HISTOLOGY

• Light microscope, camera & imaging equipment
• Water baths & incubators (Lab-line)
• Microwave, dishes and other miscellaneous items to support

-       Immunohistochemistry

-       Enzyme histochemistry

-       “in-situ” hybridisation

FORMULATION

• Eppendorf centrifuge (Brinkman 5415B), minifuges
• Mixers, sonicators & homogenizers
• Freeze dryer systems: research and high capacity (Labconco)
• Incubators: variable temperature (Lab-Line Imperial III)
• Miscellaneous: microscope, access to thermogravimetric analyzer (TA Q500TGA), and a differential scanning calorimeter (TA Q1000)

ANALYTICAL    

• Two HPLC systems (Agilent 1100): each including pump, detectors, auto-sampler, chiller, degasser, column heater 
• Quadrupole/TOF mass spectrometer with nanospray (Q-Star Elite, Applied Biosystems)
• Sample Concentrator system (Speed-Vac Plus) consisting of centrifuge (SC120A), filter, vacuum pump and cold-trap (RVT4104)
• Nitric Oxide analyzer (Sievers)
• Freeze dryer (Labconco, shared)
• Refrigerated centrifuge (Hermle Labnet Z233MK, shared) and minifuges
• Radikal also has ready access to an Agilent 1100 LC with MSD ion trap, a triple-quad ion-trap MS (Applied Biosystems AB4000 Q-Trap) for PK sample analysis, a QStar XL TOF MS with nanospray (Applied Biosystems) for high resolution and molecular formula determination, 400 and 500 MHz NMRs (Varian), thermogravimetric analyzer (TA Q500TGA), and a differential scanning calorimeter (TA Q1000)