The ZDF Rat as a Model of Type 2 Diabetes (Webinar)

Thursday, June 19 2014
11:00 am – 12:00 pm

This event was posted by Charles River Labs

Location: Online

The incidence of obesity and diabetes is reaching near epidemic proportions worldwide. Studies in appropriate animal models are very important in order to gain a better understanding of these diseases. Historically, rodents have been a mainstay of diabetes research. Various mouse and rat models have been found to mimic different aspects of obesity and obesity-driven diabetes. The ZDF rat is one such model. Because it is obese, hyperinsulinemic and develops diet-dependent diabetes, the ZDF rat embodies many of the facets of human disease. This webinar will explore the development of the diabetic phenotype in the ZDF rat. We will also demonstrate the effects of standard anti-diabetic treatments on glucose homeostasis and relevant biomarkers, as well as the effect of varying fasting times on glucose disposal.


  • Dr. Joseph Cornicelli, Director, Inflammation and Cardiovascular Pharmacology
  • Erik Rocheford, Study Director, Discovery Research Services


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