OnSite Therapeutics Inc.
Category: Drug Development
Phone: + (1) 781-799-5594
Fax: + () 978-975-7788
Location: North Andover, MA
OnSite Therapeutics, Inc. is a Massachusetts based Corporation focused on topical delivery of drug and natural product active agents. The company owns the NDA for a previously marketed tetracycline fiber for the treatment of periodontal disease. The product is named Actisite and the company will be able to return it to the market after gaining FDA approval of an NDA supplement demonstrating that a new manufacturer is in place.
The company has also licensed a patent protected, “tissue-adhesive” and active agent delivery technology invented by a Harvard Medical School professor. This platform technology is unlike other muco adhesives due to its strong and long lasting adherence properties.
Many diseases and symptoms are treated with systemic drugs which disperse throughout the body when the problem is at a specific body location. Examples include systemic antibiotics for dental or nasal infections, oral analgesics for surgical pain and systemic agents for nasal allergies. Local and topical agents are often short acting and do not remain at the point of need because the environment is constantly cleared by the body’s natural clearance functions such as saliva in the mouth and ciliary action in the nasal passages. We anticipate that our products will be safer and more effective because a lower drug dosage is possible if the residence time for a topical agent can be increased.
OnSite’s initial focus is the oral cavity even though the technology is applicable in many areas of the body. Once success has been achieved in the oral cavitiy, broader applications of the Company’s platform technology will be pursued.