Membership Directory
Sage Therapeutics
Category: Drug Development
Phone: 617-299-8383
Website: http://www.sagerx.com/
Location: Cambridge, MA
SAGE Therapeutics is a central nervous system (CNS) product focused company building a portfolio of new therapies to meet the growing unmet medical needs resulting from a range of CNS disorders, including schizophrenia, depression, pain and traumatic brain injury. SAGE Therapeutics’ proprietary Positive and Negative Allosteric Modulator (PANAM) chemistry platform targets the primary excitatory and inhibitory neurotransmitter systems in the brain and enables the development of allosteric modulators that fine tune and balance neuronal activity that is disrupted in CNS disorders. Specifically, SAGE Therapeutics is focused on non-benzodiazepine and non-glycine approaches to modulating GABA and glutamate receptors, respectively. SAGE Therapeutics’ approach leverages extensive knowledge in chemistry, molecular and in vivo pharmacology, formulation technology, biomarker data and compelling clinical proof of concept established for several of its lead programs — all of which will enable SAGE Therapeutics to accelerate the clinical development of its pipeline and bring important medicines to patients. SAGE Therapeutics is a private company launched in 2011 by a proven team of R&D leaders, renowned CNS experts and Third Rock Ventures.
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