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CreaGen Biosciences, Inc.

Category: Contract Research and Manufacturing
Phone: 781-938-1122
Fax: 781-938-1123
Website: http://www.creagenbio.com

CreaGen Biosciences is a collaborative research and development organization dedicated to providing drug discovery services and solutions to biotech and pharmaceutical companies. Our expertise spans the different functional areas of small molecule drug discovery, including synthetic, medicinal and combinatorial chemistry and structural biology. CreaGen core expertise is in medicinal chemistry, and we have the ability to synthesize compounds in parallel, both in solution and on solid phase. Our extensive experience with small molecule chemistry and structural biology allows us to offer services that include building block construction, high quality library design and compound production, primary hit identification and advanced lead optimization. The CreaGen fragment-based hit identification and lead optimization program includes crystallization of target proteins, co-crystallization of protein-fragment and protein-inhibitor complexes and solving the 3D structure(s) of target proteins and co-crystal structures. The CreaGen fragment-based hit identification and lead optimization services decrease the cost and compress the preclinical development time for our partners. Internal discovery programs at CreaGen focus on oncology and anti-infective areas. Currently, CreaGen is applying structure-based drug design techniques for the optimization of leads and the production of drug-like compounds of high value.

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