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Alexion Manufacturing, LLC

Category: Drug Development
Phone: 1-401-233-1200
Fax: 1-401-233-1210
Website: http://www.alxn.com

Alexion Manufacturing, LLC is a wholly owned subsidiary of Alexion Pharmaceuticals, Inc., a leading biotechnology company. Alexion Manufacturing, formed in 2006, employs approximately 90 people at its Rhode Island facility and was created primarily to produce Soliris™ (eculizumab), a humanized antibody that blocks complement activity. In 2007, Alexion obtained marketing approval in the U.S. and Europe for Soliris, its first product and the first treatment for paroxysmal nocturnal hemoglobinuria (PNH), a rare, disabling, and life-threatening, acquired genetic deficiency blood disorder defined by hemolysis, or destruction of red blood cells. Hemolysis in patients with PNH may be associated with severe anemia and life-threatening blood clots, as well as debilitating fatigue, impaired quality of life, renal insufficiency, pain, and shortness of breath. Alexion is also engaged in the discovery and development of new drug products, including other indications for Soliris as well as novel antibody therapeutics, aimed at treating patients with a wide array of severe disease states, including hematologic diseases, cancer, and autoimmune disorders.

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