Membership Directory

Cell Signaling Technology

Category: Research Products & Instrumentation
Phone: + () 19788672340
Website: http://www.cellsignal.com
Location: Danvers, MA

Cell Signaling Technology Inc. (CST) is a new company founded by New England Biolabs. Composed of scientists from the NEB Cell Signaling Group, CST is committed to developing innovative tools for research in Signal Transduction. CST offers a broad array of cutting edge antibody reagents to enable the discovery of protein regulation, activation and function within the cell. These powerful tools are designed to advance the understanding of Protein Function, and to open up new research directions in Neurobiology, Cancer Biology and basic Cell Biology. Scientists at CST have established a leadership position in the market for phospho-antibodies. We are committed to developing "smart" antibodies that by virtue of their binding specificity provide important biological information. These "smart" or activation state-specific antibodies reveal whether a protein and its signaling pathway are active or inactive. Our scientists have pioneered the development of phosphorylation state-specific antibodies and generated the first phospho-specific antibodies to many key signaling molecules, including the major MAP kinases and Akt. The range of these antibodies is expanding and includes cleavage- and acetylation- specific antibodies. CST has developed new methods to produce antibodies capable of detecting general protein modifications, for example, context-independent antibodies that identify phosphorylation at Tyrosine and Threonine residues as well as motif-specific antibodies that detect Phospho-Serine and -Threonine.