Membership Directory

CreaGen Biosciences, Inc.

Category: Drug Development
Phone: + (617) 304-6474
Fax: + (781) 938-1123
Website: http://www.creagenbio.com
Location: Woburn, MA

CreaGen Biosciences, Inc. is a premier chemistry-based drug discovery and development corporation that provides integrated cost effective, exceptionally high quality discovery research services to biotech and pharmaceutical companies. CreaGen?s Corporate Office is conveniently located in the Greater Boston Area, which is one of the world's most important centers for life sciences research, and is home to over 500 pharmaceutical and biotechnology companies along with world-renowned academic research institutes. Our expertise spans the different functional areas of small molecule drug discovery, including synthetic, medicinal and combinatorial chemistry and structural biology. CreaGen core expertise is in medicinal chemistry, and we have the ability to synthesize compounds in parallel, both in solution and on solid phase. Our extensive experience with small molecule chemistry and structural biology allows us to offer services that include building block construction, high quality library design and compound production, primary hit identification and advanced lead optimization. The CreaGen fragment-based hit identification and lead optimization program includes crystallization of target proteins, co-crystallization of protein-fragment and protein-inhibitor complexes and solving the 3D structure(s) of target proteins and co-crystal structures. The CreaGen fragment-based hit identification and lead optimization services decrease the cost and compress the preclinical development time for our partners. Internal discovery programs at CreaGen focus on oncology and anti-infective areas. Currently, CreaGen is applying structure-based drug design techniques for the optimization of leads and the production of drug-like compounds of high value.