Pre-Characterized Hooke Kits(TM) Eliminate Tedious Emulsion Preparation, Induce Eae And Cia

Contact: Dave Lindbergh
FOR IMMEDIATE RELEASE
   Hooke Laboratories, Inc.
   Cell: 617 501 5845
   Email: lindbergh@hookelabs.com
   http://hookelabs.com

PRE-CHARACTERIZED HOOKE KITS™ ELIMINATE TEDIOUS EMULSION PREPARATION, INDUCE EAE AND CIA
Kits Accelerate Science by Saving Time In Testing, Ensuring Successful In Vivo Experiments

Lawrence, MA, April 14 2008 — Hooke Laboratories, Inc. today announced the introduction of seven Hooke Kit™ products for immunization and induction of EAE and CIA in mice.  For the first time, scientists studying autoimmune diseases such as arthritis and multiple sclerosis will no longer have to tediously prepare emulsions and test individual reagents before starting experiments. 

The pre-characterized Hooke Kits™ introduced today are supplied in pre-filled syringes, ready to use.  They ensure reliable and consistent disease induction, as each batch is extensively tested and individually adjusted for use with different sub-strains and ages of laboratory mice.
Properly prepared emulsions are critical for reliable induction of many autoimmune disease models, such as experimental autoimmune encephalomyelitis (EAE, a mouse model of human multiple sclerosis) and collagen-induced arthritis (CIA, one of the most commonly used animal models of human rheumatoid arthritis). Hooke’s emulsions are pre-made and pre-tested to reduce the time needed to set up experiments.
Suzana Marusic, MD, PhD, President and Founder of Hooke Laboratories said “We’re really delighted with the consistent EAE and CIA induction rates we’ve been able to achieve with these kits.  By choosing a Hooke Kit™ with potency adjusted for particular mouse sub-strains and ages, our customers can induce CIA in 100% of DBA/1 mice of either Taconic or Jackson origin – even in females, which is usually extremely difficult.”
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Pre-Characterized Hooke Kits™ (page 2)
The seven Hooke Kit™ products announced today are:

Hooke Kits™ for EAE Induction:

Hooke Kits™ for Immunization:

Hooke Kits™ for CIA Induction:

Additional Hooke Kit™ products are in development, including Bovine Type II collagen emulsions for induction of CIA.

Full product details, including recommended experimental protocols and typical result data, are available on the company’s web site, http://hookelabs.com.

Hooke Laboratories offers innovations that make animal research more efficient and less expensive, with the goal of accelerating cures for human diseases while reducing and refining the use of animals.  Hooke is working to be the leading company providing tools for in vivo research.  The company was founded by immunologist Suzana Marusic, MD, PhD.
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Editors: Photos are available at http://hookelabs.com/press/2008-04-14_Hooke_Kits(tm).doc

For additional information or to schedule an interview with Dr. Marusic, please call Dave Lindbergh at 617 501 5845 (cell) or email lindbergh@hookelabs.com.