Sistemic Launches SistemQC™ microRNA-based Services for Cell Line QC

September 21, 2010

Potential for massive cost savings through downtime avoidance

Glasgow, Scotland, September 15th, 2010 – Sistemic Ltd., the fast growing UK life sciences company, today launched their patented SistemQC™ services for researchers and industry. SistemQC™ monitors cells including stem cell populations for intended or unintended change using biologically defined measures. These new product additions will support faster decision making for cell manufacturers at critical QC points within their process workflows. This allows them to proceed with confidence that their cell populations are being reliably and informatively measured. With even slightly delayed production costs often running into millions of dollars, the potential for SistemQC to have a major impact is clear.

SistemQC™ utilises Sistemic’s enabling platform technology SistemRNA™, which profiles microRNA expression providing a fingerprint of the cell system. This informs on the current cell population phenotype giving confidence that it has not deviated from the expected phenotype. SistemQC™ is suitable for use in all cells including BHK, CHO, HEK-293, NS0, PER.C6 and hybridomas.

Prof. Chris Hillier, CEO says “SistemQC™ services are being launched in response to the unmet need in the cell and stem cell fields: “In our conversations with both researchers and pharma over the last 12 months, it has become apparent that there is a real demand for reliable, information-rich QC methods to monitor cells easily and effectively and to fit within current workflow processes. Importantly, SistemQC™ not only gives a succinct read out on the status of the cells but also an insight into the underlying biological effects associated with any change detected. We are now launching our service to US customers through our Boston office and the rest of the world will follow shortly.”

About SistemRNA - SistemRNA™ is an enabling platform technology which profiles microRNA expression and utilises in-house customised algorithms which analyse the miRNA dataset that is produced when a cell is perturbed by a stimulus. This creates models/clusters of microRNA that define the phenotypic response. The microRNA response is reproducible and is a robust marker defining the biological interaction between cell and the environment. The benefit is that microRNA profiling monitors pathway control of the entire biological system of the cell in a single assay. Data is kept to a minimum where as knowledge is greatly enhanced allowing more appropriate decisions to be taken. SistemRNA™ analysis captures the dynamic response of all the cellular pathways as well as their interactions giving enhanced clarity without data overload.

About Sistemic Ltd – At the core of Sistemic lays a deep understanding of microRNA biology and profiling which in combination with customised in-house data analysis, and contextualisation programs provides a powerful tool to simplify the understanding of the biology. Sistemic’s primary business is focussed on providing innovative, problem solving services and kit based products to the life sciences research and development markets.  


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