Addgene Launches Parkinson’s Disease Plasmid Resource with The Michael J. Fox Foundation

October 4, 2012

Addgene, a non-profit organization focused on scientific sharing announced today that it is collaborating with The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to assemble a collection of plasmid DNA samples for use in Parkinson’s Disease (PD) research. This collection, the Parkinson’s Disease Plasmid Resource, will be curated and distributed by Addgene to life science researchers around the globe.

“Our mission is to make the scientific research process easier by providing access to useful tools for the functional characterization of genes. We are thrilled to work with MJFF to build this important collection for the PD research community and to play a role in the development of treatments for this devastating disease,” says Dr. Joanne Kamens, Executive Director at Addgene.

Addgene currently hosts a growing library of over 20,000 recombinant DNA molecules known as plasmids. Plasmids, a type of research tool, are widely used by life scientists to isolate and study genes to explore gene function in health and disease.  Addgene’

s service allows participating laboratories to overcome many hurdles to the reagent sharing process including sample authentication requirements, international shipping issues, data retention, technology transfer constraints and loss of samples due to personnel turnover.

The Parkinson’s Disease Plasmid Resource currently includes plasmids from over 12 research groups and is growing on a monthly basis. It includes tools for studying genes implicated in PD and mutated version of these genes that have been characterized in PD patients.  Over 500 plasmids from this collection have already been distributed to academic laboratories.  

MJFF is committed to solving problems that slow progress in finding cures for Parkinson’s Disease and has initiated multiple projects to streamline the sharing process for high quality research tools for researchers in the PD community.

“The Michael J. Fox Foundation works with a number of organizations to leverage practical solutions for sharing research tools. Working with Addgene will help consolidate these plasmids and remove hurdles associated with their widespread use,” explains Dr. Sonal Das, Associate Director of Research Programs at MJFF.  “Moreover, those plasmids that have been directly generated by MJFF will be made available to both non-profit and for-profit institutions.  By ensuring that common laboratory resources are easily accessible, MJFF hopes to accelerate PD research amongst investigators from both academia and industry,” added Dr. Das.


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