NUCLEA BIOTECHNOLOGIES RECEIVES NEW PATENT FOR USE IN COLORECTAL CANCER
Clinical testing will commence in Nuclea’s CLIA laboratory in the first quarter of 2014
Pittsfield, MA—Nuclea Biotechnologies today announced they had received a new patent for one of its immunohistochemistry (IHC) assays. U.S. Patent No. 8,580,926 B2, which was issued on November 12, 2013, is for an IHC assay used to determine if a patient diagnosed with colorectal cancer (CRC) will respond to treatment with irinotecan (CAMPTOSAR®).
Irinotecan (CAMPTOSAR®) is a first-line chemotherapeutic agent indicated for first-line therapy for patients with metastatic carcinoma of the colon or rectum. It is used in combination with 5-fluorouracil and leucovorin. The drug is a topoisomerase inhibitor and is also indicated for patients with metastatic CRC whose disease has recurred or progressed following the initial fluorouracil-based therapy. Nuclea’s test provides doctors with a valuable tool to identify those patients whose tumor is likely to respond to the drug. This is especially important as in certain populations irinotecan (CAMPTOSAR®) may be toxic.
"For the population it works for, irinotecan (CAMPTOSAR®) is a very effective drug," said Patrick J. Muraca, President and CEO of Nuclea. "This test will determine which patients with CRC will respond well to the treatment. Greater knowledge in advance of treatment allows doctors to make more informed decisions about patient care. We look forward to beginning the clinical testing of this high value test in our lab early next year."
Nuclea Biotechnologies, Inc. -- is headquartered in Pittsfield, Massachusetts with additional operations in Worcester and Cambridge, Massachusetts. Nuclea has developed and is commercializing unique diagnostic tests for colon, breast, leukemia, lung and prostate cancer. Nuclea also performs research leading to novel molecular oncology companion diagnostics for the pharmaceutical and biotechnology industries. http://www.nucleabio.com
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