Genetic Engineering and Synthetic Biology
3-credit graduate course (asynchronous delivery with additional hands-on lab requirement)
In this hybrid lecture and laboratory course, students will learn the theory and practice of genetic engineering, particularly applications to advancing discovery in the biotechnology industry. The course will cover transfer of genetic material to host organisms and modification of the hosts themselves to achieve targeted metabolic and cellular outcomes. Topics include the practical assembly of genes, gene circuits, and genomes - from classical methods like PCR and restriction enzyme cloning to modern methods like CRISPR- Cas9 editing and DNA synthesis. Lectures may also cover associated topics like recombination, primer design, combinatorial and mutagenic library assembly, and the utilities of various established and novel host cell systems. In the laboratory, students will employ individualized design strategies to affect a genetic modification using techniques like CRISPR that will yield a specified biochemical outcome.
In addition to the online asynchronous course delivery, there will be two required hands-on lab sessions on Saturday, October 5 & 19, 2019.
Tuition for this 3-credit graduate course is $4,698.