WEBINAR | Development of Mouse Pain Scales to Unlock the Sensory and Motivational Drives of Pain

Sep 30, 2021

Posted by AnaBios

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Add to Calendar + 2021-09-30 8:00 2021-09-30 9:00 America/New_York WEBINAR | Development of Mouse Pain Scales to Unlock the Sensory and Motivational Drives of Pain

Ishmail Abdus-Saboor, PhD, Assistant Professor of Biological Sciences at the Zuckerman Brain Behavior Institute at Columbia University, will present our next pain research webinar on Thursday, September 30. All of our senses—including pain—are comprised of rapid sensory detection and a motivational drive that alters behavior based on the nature of the sensory stimulus. It remains unclear how to delineate sensation versus motivation associated with pain by purely measuring behavior in animals. 

To uncover a behavioral map of the sensory-versus-motivational components of pain in mice across timescales and dimensions, Dr. Abdus-Saboor and his team used a combination of supervised and unsupervised approaches. Capturing the immediate sensory response to pain at millisecond timescales uncovered behavioral signatures that define hypersensitivity to either an innocuous or noxious mechanical stimulus. Their findings reveal that sensation versus motivational drive can be uncoupled and objectively quantified, even in animals that cannot articulate these often hidden and personal dimensions of the painful experience. There will be a live Q&A session immediately after Dr. Abdus-Saboor’s presentation. In addition, a recording of his presentation will be available shortly after the webinar. 

Dr. Abdus-Saboor received a BS in Animal Science at North Carolina A&T University in 2006, and PhD in Cell and Molecular Biology from the University of Pennsylvania in 2012. From 2012-2018, he was postdoctoral fellow at Weill Cornell Medicine and University of Pennsylvania. From 2018-2021, he was the Mitchell J. and Margo Krody Blutt Presidential Assistant Professor of Biology at the University of Pennsylvania.

Ishmail Abdus-Saboor, PhD, Assistant Professor of Biological Sciences at the Zuckerman Brain Behavior Institute at Columbia University, will present our next pain research webinar on Thursday, September 30. All of our senses—including pain—are comprised of rapid sensory detection and a motivational drive that alters behavior based on the nature of the sensory stimulus. It remains unclear how to delineate sensation versus motivation associated with pain by purely measuring behavior in animals. 

To uncover a behavioral map of the sensory-versus-motivational components of pain in mice across timescales and dimensions, Dr. Abdus-Saboor and his team used a combination of supervised and unsupervised approaches. Capturing the immediate sensory response to pain at millisecond timescales uncovered behavioral signatures that define hypersensitivity to either an innocuous or noxious mechanical stimulus. Their findings reveal that sensation versus motivational drive can be uncoupled and objectively quantified, even in animals that cannot articulate these often hidden and personal dimensions of the painful experience. There will be a live Q&A session immediately after Dr. Abdus-Saboor’s presentation. In addition, a recording of his presentation will be available shortly after the webinar. 

Dr. Abdus-Saboor received a BS in Animal Science at North Carolina A&T University in 2006, and PhD in Cell and Molecular Biology from the University of Pennsylvania in 2012. From 2012-2018, he was postdoctoral fellow at Weill Cornell Medicine and University of Pennsylvania. From 2018-2021, he was the Mitchell J. and Margo Krody Blutt Presidential Assistant Professor of Biology at the University of Pennsylvania.

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