As a global hub for life sciences, Boston is home to some of the most advanced research institutions and biopharma companies. For researchers in this thriving ecosystem, finding the right biorepository to support their work is essential. With so many options available, how do you select a facility that meets your needs? This guide will walk you through the key factors to consider when choosing a biorepository in Boston.
Why the Right Biorepository Matters
Biorepositories play a critical role in ensuring the integrity and accessibility of biological specimens. Whether you are working on clinical trials, drug development, or advanced therapies, the quality of your repository can directly impact your research outcomes.
The right biorepository should offer:
- Secure and compliant storage facilities
- Efficient retrieval and distribution of samples
- Advanced technologies for sample tracking and data integration
Key Factors to Consider
1. Sample Types and Storage Capabilities
Different studies require different storage solutions. Confirm that the biorepository you choose can accommodate your specific sample and material types, such as:
- Human or animal biologics (blood, tissues, cells, DNA, RNA, plasma, forensics, and fluids)
- Biologic test materials (reagents, liquids, washes, and powders)
- Research materials (slides, paraffin blocks, and powders)
- Agricultural plant banks (seeds, tissues, soil, and sand)
- Active pharmaceutical ingredients, bulk drug substances, and finished therapeutics
Check for specialized storage environments to ensure the longevity of your specimens.
- Ambient and controlled room temperature (CRT)
- Freezer/refrigeration (+5°C to -20°C)
- Ultra-low freezer (-40°C to -80°C)
- Liquid nitrogen (-150°C to -196°C)
2. Regulatory Compliance
Compliance with regulatory standards is non-negotiable. Verify that the biorepository adheres to:
- FDA regulations
- Good Clinical Practices (GCP)
- 21 CFR Part 11 regulations
- International Society for Biological and Environmental Repositories (ISBER) guidelines
- International and domestic ethical guidelines and regulations
Ask for documentation or certifications to ensure the facility meets industry standards.
3. Location and Accessibility
For Boston-based researchers, proximity can be used to your benefit. A local biorepository allows for faster access to stored specimens, and additional peace of mind knowing that your samples are nearby. Consider if the repository offers:
- Transport logistics
- Availability of courier services for same-day needs
- Tours of their nearby facility
- Couriers that have been vetted and can accommodate any logistics needs
4. Technology and Data Management
Modern biorepositories leverage technology to enhance sample tracking, data integration, and reporting. Manual processes are reduced, causing less errors as well. Look for features such as:
- Barcode or RFID tracking systems
- Automated storage systems and processes
- Real-time inventory management
- Secure digital platforms for data access
- Integration with laboratory information management systems (LIMS)
5. Scalability and Flexibility
As your research evolves, your storage needs may change. Choose a biorepository that offers:
- Flexible storage options, including infrastructure to support a wide range of temperatures and sample types
- Sample management support at your site, off-site, or both
- Room for expansion, including in additional states or countries
- Customizable services, such as sample preparation or data analysis
6. Reputation and Track Record
Research the repository organization’s history and client base. Consider:
- Partnerships with leading institutions globally
- Positive reviews and testimonials
- Case studies showcasing successful collaborations
7. Cost, Quality, and Value
While cost is an important factor, the security and integrity of your samples and materials is integral to your work. Assess the value of the repository by considering what is included in the service package:
- Advanced sample management and storage processes
- Quality management system (QMS) built to support compliance with stringent GxP requirements
- Transparent and comprehensive data management
- Retrieval times that meet your organization’s needs
Questions to Ask When Evaluating a Biorepository
- What types of samples do you specialize in storing?
- What security measures are in place to protect specimens and data?
- How do you ensure regulatory compliance?
- What technologies do you use for inventory management and tracking?
- Can you provide references or case studies?
- Are there any additional fees I should be aware of?
What’s Next?
Choosing the right biorepository is a critical step in ensuring the success of your research. By considering factors like storage capabilities, compliance, technology, and reputation, you can select a facility that aligns with your needs and helps support the groundbreaking discoveries that are born from Boston’s vibrant life sciences ecosystem.
For all the features above and more, consider partnering with Azenta Life Sciences and our new Boston-area repository to free up lab space and get your local samples within a day. Specifically designed to provide storage for a wide range of needs, our repository supports materials and logistics for active clinical trials, product manufacturing, and research samples you need on occasion. Learn more about how Azenta biorepository storage solutions would benefit your organization, or request a tour to see it for yourself!