Peptides have emerged as indispensable tools in modern drug discovery, playing a central role in areas such as oncology, metabolic disorders, targeted delivery, and protein–protein interaction modulation. With over 80 peptide-based drugs approved globally and hundreds more in clinical pipelines, the demand for reliable, scalable, and fast Custom Peptide Synthesis services has never been greater (Source 1).
Their unique ability to precisely modulate biological pathways has driven rapid market expansion: from around $50 billion in global sales in 2019, accounting for roughly 5% of the total pharmaceutical market, to an estimated $117 billion in 2024, $140.85 billion in 2025, with projections reaching over $260 billion by 2030 (CAGR ≈10.8%) (Source 2) (Source 3)
However, while scientific innovation around peptides is advancing rapidly, the operational challenges of sourcing peptides, especially in early-stage research, remain a critical challenge for researchers. Delays in acquiring custom peptides can slow down SAR studies, impact screening cascades, and ultimately shift timelines for IND-enabling activities.
In a domain where each week of delay can result in significant opportunity cost, particularly in competitive or patent-sensitive programmes, speed and reliability in peptide delivery are essential, not optional. Traditional synthesis services often span 3-4 weeks or more, with additional time lost to quote cycles, QC inconsistencies, or incomplete analytical data.
Recognizing this gap, o2h Discovery has launched the Peptide Guarantee Programme, with the aim to deliver custom linear peptides (≥95% purity, ≤20 amino acids) in 2 weeks from project initiation, complete with HPLC, MS, and Certificate of Analysis. If it’s delayed, it’s on us.
This initiative is not just about faster turnaround; it’s a strategic response to the evolving pace of drug discovery, especially in fast-moving fields like bi-functional molecules, peptide–drug conjugates (PDCs), and next-gen therapeutic constructs, where dependable building blocks like peptides must arrive on time and of high quality.
The Benefits of Fast Custom Peptide Delivery: Scientific and Operational Impact
In early-stage discovery, agility is as critical as scientific accuracy. A rapid, reliable supply of high-purity peptides can significantly accelerate:
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Structure–Activity Relationship (SAR) Studies: Researchers often require multiple peptide analogs within tight timeframes. Fast custom peptide synthesis enables real-time iteration, improving hit-to-lead progression.
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Bioconjugation Experiments: For bi-functional or conjugated molecules, peptide delivery speed directly influences the ability to test linkers, payloads, or warheads at pace.
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Screening Campaigns: Timely availability of peptides ensures integration into HTS and cell-based assays without scheduling disruptions.
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Cross-Functional Coordination: When peptide delivery aligns with biology, DMPK, and formulation teams’ schedules, downstream efficiencies multiply.
Operationally, a 2-week synthesis timeline reduces idle lab time, shortens project cycles, and creates predictability in planning. This is especially valuable for startups and biotech partners operating within fixed milestones or investor timelines.
Use Cases of Fast Custom Peptide Synthesis Services Across Therapeutic Modalities
Fast peptide synthesis Services play a critical role in programmes where timelines are tight and data generation is time-sensitive:
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Bi-Functional Modality Programmes: Many targeted degradation or multi-target strategies involve peptide-based ligands or linkers that must be delivered quickly to test new functionalities or optimise binding interactions.
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Peptide–Drug Conjugates (PDCs): Early studies in cancer and infectious disease often require linker–peptide combinations that are difficult to source quickly through standard CRO pipelines.
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Macrocycles and Stapled Peptides: In target classes like transcription factors or intracellular PPIs, non-linear peptides (which may begin as linear precursors) often need rapid evaluation and iteration.
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Neoantigen Vaccine Design: Personalised immunotherapy depends on fast peptide synthesis Services to match patient-specific tumor profiles; delays in this space can derail treatment windows.
How o2h Discovery Delivers on the 2-Week Peptide Guarantee
With the o2h Peptide Guarantee Programme, our goal is simple: Deliver high-quality peptides in 2 weeks. If delayed, it’s on us
o2h Discovery’s peptide platform is built on internal chemistry expertise, streamlined procurement, and optimized parallel synthesis workflows. The 2-week guarantee includes:
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Ultra-Fast Custom Peptide Synthesis Services: High-quality peptides delivered in 2 weeks. If delayed, it’s on us. T&C applied
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Highly Experienced Peptide Chemists: Work with our expert scientists with vast experience in synthesising and optimising complex peptide molecules with efficiency
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End-to-End Peptide Solutions: From custom synthesis and complex modifications at mg to gram scale, to purification, analysis, and characterisation, we handle it all with precision
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Cutting-Edge Equipment & Advanced Capabilities: o2h’s peptide facility is equipped with Biotage Syro I, CEM Liberty Blue, and more for fast, high-quality peptide production
This initiative is designed to accelerate the drug discovery journey for small-molecule-focused biotech organisations, academic researchers, and pharma companies by providing peptides with speed, precision, and reliability.
Our expertise in fast peptide synthesis supports the development of innovative therapies that address unmet medical needs, helping advance groundbreaking science that improves human health and the environment.
Note: Acceptance of any order request under this programme is subject to a technical feasibility review by our scientific team. A final decision will typically be communicated in approximately 3 working days.
Industry Benchmarks and Why This Matters
While many CROs offer custom peptide synthesis, typical turnaround times range from 3–5 weeks, with added time for QC, communication gaps, or outsourcing logistics. In contrast, o2h’s integrated offering, developed in-house and delivered at scale, brings a faster and more predictable alternative, without compromising quality or analytical depth.
With rising demand for fast, scalable drug discovery support across the UK, US, and Europe, this initiative places o2h Discovery at the forefront of responsive custom peptide synthesis. For partners pursuing aggressive timelines, fast-moving pipelines, or critical path deliverables, the o2h Peptide Guarantee is more than a promise; it’s a delivery commitment.
If you’re working on a complex peptide therapeutic and require dependable, scalable support to accelerate synthesis and development, this programme is for you. Click here to discuss your specific project needs with our scientific team.
About o2h Discovery
Founded in 2005, o2h Discovery is a multi-award-winning CRO with a multi-modality integrated drug discovery platform, operating from Cambridge, UK, and Ahmedabad, India. We execute hit-to-lead optimisation programmes leading into patent and IND filing, with deep expertise in discovery chemistry, biology, pharmacology, and the ongoing project management of pre-clinical development.
We have experienced scientists who deliver a comprehensive range of custom peptide synthesis services, from small quantities of a few milligrams to larger amounts at gram scale. Our capabilities go beyond standard fast custom peptide synthesis services, offering specialised peptide modification services to customise and optimise peptides for diverse drug discovery programmes. Our clients include large pharma companies, leading academic institutions, and biotech firms. We’re also available on Scientist.com.
o2h Discovery’s large team of experts also delivers high-quality services, covering DMPK, scale-up/PR&D, PROTAC,s (Protac Synthesis Services) LNPs, various assays including ChamelogK, supporting organizations of all sizes with cost-effective solutions from target validation all the way to IND-enabling studies.
Our Peptide Range & Modifications
In addition to synthesis, our experienced team of chemists also excel in performing a wide range of peptide modifications, including but not limited to the following:
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Linear – long chain peptides
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Branched Peptides
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Succinylated Peptides
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Stapled Peptides
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Macrocyclic Peptides
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Acetylated Peptides
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PEGylated Peptides
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Head-to-Tail Cyclization
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Di-sulphide bond formation
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Lactam ring formation
We have an experienced team of dedicated analytical scientists and labs equipped with the latest instruments to manage and achieve high ‘speed’ delivery of peptide projects. We also offer a comprehensive suite of biology services, including FP, SPR, FRET, HCI, and flow cytometry. Our team has also validated a range of peptide-focused ADME assays, including plasma protein binding (PPB), plasma stability, and permeability studies.
Frequently Asked Questions (FAQs)
Q. What types of peptides are covered under the 2-week guarantee?
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Standard linear peptides up to 20 amino acids in length and up to gram in quantity are covered under our guarantee.
Q. What purity levels do you provide for peptides?
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All peptides are synthesized at ≥95% purity and come with complete analytical data, including HPLC, MS, and a Certificate of Analysis (COA).
Q. Is the 2-week Peptide Guarantee available globally?
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Yes, the o2h Peptide Guarantee is available to biotech and pharma companies worldwide. Delivery timelines depend on customs and shipping partners.
Q. Are all peptide synthesis projects eligible for the 2-week guarantee?
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No, project eligibility is determined after internal review by the o2h Discovery team. Non-standard peptides or complex sequences may not qualify; in such cases, a custom Fee-for-Service (FFS) proposal will be provided with tailored timelines.
Q. How do I initiate a custom peptide synthesis project with o2h Discovery?
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To begin, please fill out the short inquiry form to contact our scientific team with your peptide sequence and any specific requirements. After a quick feasibility review (within ~3 working days), our team will confirm the scope and timeline.
Looking for more detailed answers? Explore our detailed FAQ page for technical scope, eligibility criteria, and order process details.
Have more questions?
Reach out to our peptide chemistry team at discovery@o2h.com or submit a request via the short form on o2h Discovery Peptide Guarantee to discuss your project requirements.