Q. What is the o2h Peptide Guarantee Programme?
A. The o2h Peptide Guarantee Programme is a global initiative by o2h Discovery offering custom fast peptide synthesis delivered within 2 weeks of project initiation. It is designed to accelerate early-stage drug discovery by ensuring fast, high-quality, and reliable peptide delivery.
Q. What types of peptides are covered under the 2-week guarantee?
A. Standard linear peptides up to 20 amino acids in length and up to a gram in quantity are covered under our guarantee.
Q. What purity levels do you provide for peptides?
A. All peptides are synthesized at ≥95% purity and come with complete analytical data, including HPLC, MS, and a Certificate of Analysis (COA).
Q. What is the minimum and maximum scale of peptide synthesis?
A. We offer flexible scales, ranging from 1 mg to gram quantities, tailored to your project requirements.
Q. Can you make modified or more sophisticated peptide species, such as cyclic peptides, bi-functional/bi-valent, peptide drug conjugates, modifications such as PEGylation and PTMs, labelled peptides, and so on?
A. Yes, we could make the core linear peptide under the guarantee, but the modifications would usually be outside the scope of the o2h peptide guarantee and we would perform this aspect under our usual service model. Please contact us to discuss how we would approach this for you.
Q: Can o2h Discovery synthesize peptides using non-natural amino acids?
A. Yes, we offer peptide synthesis using a wide range of non-natural amino acids to support complex and custom requirements.
Q. Is the 2-week Peptide Guarantee available globally?
A. Yes, the o2h Peptide Guarantee is available to biotech and pharma companies worldwide. Delivery timelines depend on customs and shipping partners.
Q. When does the 2-week peptide turnaround time begin?
A. The 2-week turnaround time starts from the date of final project confirmation and material availability. It refers specifically to the synthesis phase and does not include shipping time.
Q. Are all peptide synthesis projects eligible for the 2-week guarantee?
A. No, project eligibility is determined after internal review by the o2h Discovery team. Non-standard peptides or complex sequences may not qualify; in such cases, a custom Fee-for-Service (FFS) proposal will be provided with tailored timelines.
Q. What other services does o2h Discovery provide?
A. Founded in 2005, o2h Discovery is a multi award-winning CRO with a multi-modality integrated drug discovery platform, operating from Cambridge, UK, and Ahmedabad, India. In addition of fast peptide synthesis services, o2h Discovery’s large team of experts delivers high-quality services, covering chemistry, biology, DMPK, scale-up/PR&D, PROTAC,s (Protac Synthesis Services) LNPs, various assays including ChamelogK, supporting organizations of all sizes with cost-effective solutions from target validation all the way to IND-enabling studies.
Our chemistry team excels in preparing high-quality small-molecule NCEs (Novel Chemical Entities) using diverse methodologies, including single synthesis, multi-step synthesis, and the parallel construction of focused libraries for hit-to-lead and lead optimization projects. We ensure complete characterization of all compounds, providing high-field NMR, mass, and purity data through LC-MS/HPLC/GC.
In biology, our experienced team conducts cutting-edge assays, target validation, and mechanism-of-action studies using advanced technologies such as flow cytometry and high-content imaging. This integrated approach allows us to offer comprehensive drug discovery services, from hit identification to preclinical development. Read our recent blog on why fast peptide synthesis services matter in drug discovery.
Let’s talk about your project. We’d love to hear your discovery pipeline and explore how we can help in other ways too. You may also reach out to us at discovery@o2h.com