Member Spotlight: Unravel Biosciences, Inc.

Sep 28, 2026

Unravel is a clinical-stage biotech company whose Agile Medicine approach brings patients into drug discovery from the start, using individual patient RNA to power AI-enabled therapeutic mechanism discovery. The approach offers patients potential treatments today with off-label use of existing medications while unlocking clinical signals with unprecedented speed. Unravel has delivered direct-to-patient personalized medicine serving over 1,500 individuals with 120 different disorders. Unravel is also conducting two clinical trials of RVL-001 for treatment of Rett and Pitt Hopkins syndromes and is developing four additional therapies to treat other complex disorders, while pursuing ALS treatments in a global collaboration as a recipient of the ALS Longitude Prize.

MassBio Member Spotlight: Unravel Biosciences, Inc.

Location: 196 Boston Ave, Suite 1000, Medford, MA

Therapeutic area(s): Complex and rare disorders, personalized medicine 

Leadership:

  • Richard Novak, CEO
  • Frederic Vigneault, Chief Scientific Officer
  • Neal Muni, Chief Medical Officer

Website: unravel.bio

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