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Paralog Therapeutics logo
MassBio Spring 2025

Paralog Therapeutics

Watertown, MA

Paralog Therapeutics is a pre-clinical stage precision medicine company focused on the development of anti-cancer therapies. Paralog Therapeutics’ mission is to identify and leverage synthetic vulnerabilities in cancers that carry specific gene alterations.

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State 4 Therapeutics logo
MassBio Spring 2025

State 4 Therapeutics

New Haven, CT

State 4 Therapeutics is developing oral small molecule therapies that synergize with nutrient-stimulated hormones for the treatment of obesity and metabolic diseases. 

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TMAB Therapeutics logo
MassBio Spring 2025

TMAB Therapeutics

Houston, TX
LinkedIn

TMAB Therapeutics is developing first-in-class multi-specific antibodies designed to enhance immune activation while inhibiting angiogenesis within the solid tumor microenvironment. By simultaneously targeting CD5L and EGLF6, TMAB Therapeutics aims to overcome adaptive resistance to anti-VEGF and anti-PD1 therapies, offering a novel treatment approach for non-small cell lung cancer, microsatellite-stable colorectal cancer, and high-grade serous epithelial…

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TATUM Bioscience logo
SCbio Spring 2025

TATUM Bioscience

Sherbrooke, Canada (Qc) Oncology & immuno-oncology
LinkedIn

Immuno-oncology, and the advent of checkpoint inhibitors, profoundly revolutionized the treatment of cancers by making cancer-free outcome a reality. Unfortunately, after more than a decade of drug development, only 20% of patients are responding to these blockbuster immunotherapies, which leaves 80% of patients without any therapeutic solutions.  At TATUM bioscience we are dedicated to solving…

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SiNON Nano Sciences logo
SCbio Spring 2025

SiNON Nano Sciences

Durham, NC Neuroscience
LinkedIn

SiNON Nano Sciences is a biotechnology company pioneering carbon-based nanotechnology for targeted drug delivery, with a primary focus on Central Nervous System (CNS) diseases. Our patented Carbon Nano Particle (CNP) platform is designed to efficiently cross the blood-brain barrier (BBB), enabling safer, more precise, and highly effective treatment delivery for neurological disorders, oncology, and other…

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Sebastian BioPharma logo
SCbio Spring 2025

Sebastian BioPharma

Beverly, MA Oncology & immuno-oncology
LinkedIn

Sebastian BioPharma is a preclinical-stage biotechnology company driven by a singular mission: to develop groundbreaking biologics that offer new therapeutic options for millions of cancer patients. The company utilizes compelling proof-of-concept data from multiple innovative therapeutic strategies and a versatile ‘plug-and-play’ antibody-oligonucleotide conjugate (AOC) platform to enhance the efficacy of immune checkpoint blockade (ICB) therapies…

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OsteoCure Therapeutics, Inc logo
SCbio Spring 2025

OsteoCure Therapeutics, Inc

Durham, NC Biologics
LinkedIn

OsteoCure Therapeutics is a Duke University spinout and JLABS company focused on developing advanced therapies to address critical unmet needs in bone health and regeneration. Leveraging cutting-edge research, the company specializes in novel combination products designed to accelerate bone healing, mitigate pain, improve patient outcomes, and reduce recovery times for those suffering from orthopedic injuries…

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Lipo-Immuno Tech, LLC logo
SCbio Spring 2025

Lipo-Immuno Tech, LLC

Mount Pleasant, SC Oncology & immuno-oncology

Company Vision: To unite drug development, forward-thinking mechanistic science, and clinical application in order to create novel therapeutics that cure diseases. Overview: Lipo-ImmunoTech was founded on the goal of advancing anti-cancer strategies, which are also effective in treating some neurodegenerative disorders, like Alzheimer’s Disease, that have strong mechanistic data and can dramatically benefit patient health.…

  • Besim Ogretmen, PhD

    Co-Founder and CEO, Lipo-Immuno Tech

  • Shikhar Mehrotra, PhD

    Co-Founder and CSO, Lipo-ImmunoTech

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Genicity Ltd logo
SCbio Spring 2025

Genicity Ltd

Galway, Ireland Oncology & immuno-oncology
LinkedIn

Genicity, founded in 2021 by Muhammad Yassin, MD, PhD, and Muneer Sawaied, MD, is an innovative Galway-based cell therapy company. Recognized with the Life Sciences and Healthcare Award at the Irish Times 2023 and the Merck Prize at the BioTech BootCamp, Genecity was also a finalist for the Golden Ticket from the American Cancer Society.…

  • Muhammad Yassin

    MD, PhD Chief Scientific Officer, Co-Founder

  • Muneer Sawaied, MD

    Chief Operating Officer, Co-Founder

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D2B3 logo
MassBio Fall 2024

D2B3

Branford, CT Biologics, Neuroscience, Platform

Over 98% of all drugs struggle to cross the Blood-Brain Barrier (BBB), hindering their usability against CNS diseases. D2B3’s breakthrough is a patented human monoclonal antibody (Mab), that transiently and highly specifically opens the BBB, achieving high drug penetration to the brain. The lead asset D2B3-01 has shown exceptional performance in in vivo proof of…

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HarborSite logo
MassBio Fall 2024

HarborSite

Boston, MA Cell & gene therapy, Platform

HarborSite, a Harvard/Wyss Institute spinoff, is pioneering a safe and efficient gene insertion technology to provide curative treatments for rare genetic and common disorders. By engineering compact, simple yet potent enzymes — recombinases — HarborSite can efficiently and precisely integrate large DNA cargos into genomic safe harbors for robust and durable therapeutic gene expression, with…

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Lybra Bio logo
MassBio Fall 2024

Lybra Bio

Cambridge, MA Biologics, Immunology & inflammation, Platform
LinkedIn

Lybra Bio is reshaping the treatment landscape of Autoimmune Skin Diseases. They are developing innovative therapeutics platforms aiming to restore the skin’s immune equilibrium in patients suffering from Autoimmune Skin Diseases. Lybra Bio’s first platform combines clinically validated cytokines loaded into an advanced microneedle patch for superior efficacy and patient compliance while bypassing systemic side…

  • Jamil R. Azzi, PhD, MD

    Academic Co-founder

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